[ESH2010]肾素抑制剂心血管保护作用机制及糖尿病合并高血压患者降压策略——Bryan Williams教授采访Interview with Dr. Bryan Williams
《国际循环》:近期一些新研究已证实了直接肾素抑制剂阿利吉仑的抗高血压作用更好,且其心血管保护作用也很优秀。
<International Circulation>:Recently some new studies have demonstrated a better antihypertensive effect with aliskiren, a direct renin inhibitor, and its cardiovascular protective function is also excellent.
Williams教授:我认为,它就像很多这种新型药物一样,现在我们必须等待,直到我们看到来自很多正在进行的终点试验的证据,这些试验旨在证实它将产生今天我们讨论的我们在其他药物中已观察到的保护作用。我认为它将会被证实有这种保护作用,且我认为它作用时间长。它可能是与CCB或CCB加利尿剂一起联合的一种非常有效地药物。它应该是令人感兴趣的。
Prof. Williams: I think it’s like a lot of these newer drugs, we have to wait now until we see the evidence from the many outcome trials that are ongoing to confirm that it will reproduce the protection that we’ve seen with other drugs that we’ve been talking about today. I think it will. And I think it has a long duration of action. It is likely to be a very effective drug in combination with a CCB or in combination with both CCB and a diuretic. It should be interesting.
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